What does KYPO mean?
Keep Your Pants On
Other definitions of KYPO:
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How to use the term KYPO:
There are no example uses of KYPO at this time. We would greatly appreciate your contribution if you would like to submit your own!
More slang terms:

I&I
Intercourse & Inebriation

TTMF
Ta, Ta, MOFO

INBD
It's No Big Deal

LSHMBH
Laughing So Hard My Belly Hurts